Biycycle Sharing System
Drug Eluting Device for Treatment of Eye Diseases
Who: William Pitt
What: A contact lens loaded in a unique manner with a therapeutic drug
This method is useful for loading a hydrophobic hydrogel contact lens, such as a “silicone hydrogel” contact lens, with a hydrophobic drug. Current methods are non-existent or very laborious and time consuming to load hydrophobic drugs into a hydrophobic lens. This method loads the hydrophobic drug in minutes instead of hours or days. While the loading method is not novel (BYU published it several years ago), its use to load a hydrophobic drug into a silicone hydrogel contact lens produces a novel device that is useful for sustained drug delivery.
This technology could be applied to load drugs into contact lenses during or after manufacturing. It could be used to load hydrophobic durgs into other hrdrophobic hydrogel materials for other applications of drug delivery.
The purpose of the invention is to provide a constant release of drug to the eye. Current methods of applying drug to the eye include eye drops and ey ointments. In both of these methods a large amount of drug is applied to the eye at initial application, and then the excess drug is washed away in the tears as the eye drops are flushed from the eye by normal tear flow. Applying an ointment prolongs the delivery, but the gel is often difficult to self-apply by older people and is eventually washed from the eye also. An ocular insert provides a reservoir from which sustained delivery can occur, but the insert is irritating to the eye, and difficult to self-insert by older people.
The most important advantage is that the drug elutes slowly and constantly over many days from a contact lens, so that the eye is continually bathed in a low and therapeutically correct concentration of the needed drug. Some silicone hydrogel contact lenses can be worn during sleep, so drug delivery occurs continually, even during sleep. The lens can be replaced on a daily, weekly, or monthly schedule.
Many people wear contact lenses, or have worn them. These people may be more comfortable using a sustained release device that is a comfortable contact lens, rather than inserting a solid drug depot, or inserting a gel. Furthermore, the contact lens can provide refractice correction if needed. The invention is to be used by people with eye diseases that can be treated by hydrophobic or amphipathic drugs.
For more information, contact Mike Alder (801-422-3049)
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Who: Michael Dunn
What: A super premium frozen dairy-dessert. Offering versatility to the frozen treat industry.
Gelato desserts have increased in popularity in recent years due to their rich and creamy nature. Frigelato expands the scope of uses by allowing it to be served/purchased as frozen gelato, or served/purchased from refrigerated temperatures while still preserving the eating properties of a traditional gelato. The fact that this delicious product can be served as either a frozen or refrigerated dessert dramatically increases its’ versatility and opens up a variety of usage occasions appealing to an expanded target market. Initial taste tests have resulted in positive feedback from the direct consumer, both in texture and taste qualities, as well as in the versatility of the product.
Althought the formulation is unique, the product can easily be manufactured using standard equipment available in any dairy plant having ice cream process capabilities. This product even has the capability oto be run through commercial pasteurizers and homogenizers.
This product is for those who enjoy indulging in deliciously rich dairy desserts. However, the super-premium nature of this product would dictate that the primary focus of advertising and marketing efforts would be directed at adults. This product has huge marketing potential. A recent Mintel report indicates that the ice cream industry is being affected by the slumping econcomy. This has affected the dairy industry as a whole. The growth in the market is from sales of frozen yogurt, sherbet, sorbets, ices, and frozen novelties. The vast amount of this growth comes directly from the frozen novelty sector. Frigelato would be recognized as an innovative novelty and assist in the continued growth of this section of the market.
For more information, contact Mile Alder (801-422-3049)
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Minimally Invasive Surgical Retractor
Who: Larry Howell
What: A simpler, safer, and more cost efficient means of handling organs during laparoscopic surgery.
Current laparoscopic surgery technologies utilize expanding mechanisms that, once inside the body, expand and hold a certain organ during the surgery. Compared to current options the retractor offers an improved ability to grip organs, as well as be able to apply the necessary force to the organ without deforming or bending it. It also reduces the number of sharp edges.
This retractor provides improved grip, rigidity and safety utilizing compliant techniques developed by BYU’s compliant mechanism lab. It can fit into spaces as small as 5-12mm, and once inside expands safer than current options. As well as having these benefits, it is also easier to manufacture thus reducing manufacturing costs. This may open doors to disposable options as well. It is also easier to clean than current options with less moving parts and sharp edges.
Potential customers for this product include companies involved in MIS (Minimally Invasive Surgery) and associated medical devices.
For more information, contact Spencer Rogers (801-422-3676)
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